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Title   인체 대장암세포간 합착에서 암태아성 항원 ( CEA ) 의 기능적 역할 ( Functional Role of Carcinoembryonic Antigen in the Intercellular Adhesion of Human Colorectal Carcinoma Cell Lines )
Publicationinfo   1993 Jan; 025(06): 855-865.
Key_word   Carcinoembryonic antigen, Cell sdhesion, Colorectal carcinoma
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Abstract   Human Carcinoembryonic antigen(CEA) has been known to have an important role in intercellular adhesion of human colorecatal carcinoma cells The purpose of this study was to verify the functional role of CEA as an adhesion molecule in respect to the sequential stream of colorectal tumor cell biology using our consecutive studies reported and ongoing. Two CEA-ex- pressing carcinoma cell lines(KM-12c and CCL-l88) and the CEA cDNA transfectants(CEA-I, 17A) bound to CEA, while the CEA-nonproducing carcinoma cell line(Clone A) and the parental CHO cell lines did not. Monoclonal antibodies to epitopes on CEA that crossreact with nonspecific crossreacting antigen
저 자   김진천(Jin Cheon Kim),이시세이찌(Seilchi Ishii),토마스피터(Peter Thomas),스틸글렌(Glenn Steele),제섭존(John M . Jessup)